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scRepertoire 2: Enhanced and efficient toolkit for single-cell immune profiling

Single-cell adaptive immune receptor repertoire sequencing (scAIRR-seq) and single-cell RNA sequencing (scRNA-seq) provide a …

Qile Yang, Ksenia R. Safina, Kieu Diem Quynh Nguyen, Zewen Kelvin Tuong, Nick Borcherding

scRepertoire 2: Enhanced and efficient toolkit for single-cell immune profiling

Single-cell immune repertoire analysis

Single-cell T cell and B cell antigen receptor-sequencing data analysis can potentially perform in-depth assessments of adaptive immune …

Sergio Irac, Megan Sioe Fei Soon, Nick Borcherding, Zewen Kelvin Tuong

Ibex

Autoencoder for single-cell BCR

scRepertoire v2

A toolkit for single-cell immune profiling

Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells

B cell responses are critical for antiviral immunity. However, a comprehensive picture of antigen-specific B cell differentiation, …

Nimitha R Mathew, Jayalal K Jayanthan, Ilya V Smirnov, Jonathan L Robinson, Hannes Axelsson, Sravya S Nakka, Aikaterini Emmanouilidi, Paulo Czarnewski, William T Yewdell, Karin Schön, Cristina Lebrero-Fernández, Valentina Bernasconi, William Rodin, Ali M Harandi, Nils Lycke, Nick Borcherding, Jonathan W Yewdell, Victor Greiff, Mats Bemark, Davide Angeletti

SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2

In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast-derived mAbs from individuals who received …

Fatima Amanat, Mahima Thapa, Tinting Lei, Shaza M. Sayed Ahmed, Daniel C. Adelsberg, Juan Manuel Carreño, Shirin Strohmeier, Aaron J. Schmitz, Sarah Zafar, Julian Q. Zhou, Willemijn Rijnink, Hala Alshammary, Nick Borcherding, Ana Gonzalez Reiche, Komal Srivastava, Emilia Mia Sordillo, Harm van Bakel, Jackson S. Turner, Goran Bajic, Viviana Simon, Ali H. Ellebedy, Florian Krammer

SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2

scRepertoire: An R-based toolkit for single-cell immune receptor analysis

Single-cell sequencing is an emerging technology in the field of immunology and oncology that allows researchers to couple RNA …

Nick Borcherding, Nicholas Bormann, Gloria Kraus

scRepertoire: An R-based toolkit for single-cell immune receptor analysis