Publications

(2025). scRepertoire 2: Enhanced and efficient toolkit for single-cell immune profiling. In PLoS Computational Biology.

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(2025). dandelionR: Single-cell immune repertoire trajectory analysis in R. In Computational and Structural Biotechnology Journal.

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(2025). Myelin-reactive CD8+ T cells influence conventional dendritic cell subsets towards a mature and regulatory phenotype in experimental autoimmune encephalomyelitis. In Journal of Neuroinflammation.

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(2025). TIFAB modulates metabolic pathways in KMT2A::MLLT3−induced AML through HNF4A. In Blood Advances.

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(2024). Leveraging single-cell transcriptomic data to uncover immune suppressive cancer cell subsets in triple-negative canine breast cancers. In Frontiers in Veterinary Science.

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(2024). CD8+ T-cell differentiation and dysfunction inform treatment response in acute myeloid leukemia. In Blood.

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(2024). Mitochondria transfer-based therapies reduce the morbidity and mortality of Leigh syndrome. In Nature Metabolism.

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(2024). CD4+ T cells exhibit distinct transcriptional phenotypes in the lymph nodes and blood following mRNA vaccination in humans. In Nature Immunology.

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(2024). Single-cell transcriptomics unveil profiles and interplay of immune subsets in rare autoimmune childhood Sjögren's disease. In Communications Biology.

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(2024). Single-cell immune repertoire analysis. In Nature Methods.

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(2024). Intratumoral T-cell receptor repertoire composition predicts overall survival in patients with pancreatic ductal adenocarcinoma. In Oncoimmunology.

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(2024). Type I Interferon Drives a Cellular State Inert to TCR‐Stimulation and Could Impede Effective T‐Cell Differentiation in Cancer. In European Journal of Immunology.

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(2023). T Cell Clonal Analysis Using Single-cell RNA Sequencing and Reference Maps. In BioProtocol.

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(2023). Molecular techniques drive cutting edge advancements in management of cutaneous T cell lymphoma. In Frontiers in Immunology.

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(2023). Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity. In Nature Immunology.

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(2023). Multifunctional cytokine production marks influenza A virus-specific CD4 T cells with high expression of survival molecules. In European Journal of Immunology.

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(2023). Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non-small cell lung cancer. In Science Translational Medicine.

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(2023). Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity. In Cancer Cell.

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(2023). CD5 expression by dendritic cells directs T cell immunity and sustains immunotherapy responses. In Science.

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(2022). Stromal reprogramming by FAK inhibition overcomes radiation resistance to allow for immune priming and response to checkpoint blockade. In Cancer Discovery.

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(2022). Isoflavone consumption reduces inflammation through modulation of phenylalanine and lipid metabolism. In Metabolomics.

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(2022). HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia. In Nature Communications.

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(2022). Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood. In Cell Metabolism.

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(2022). Single-cell analysis of Sézary syndrome reveals novel markers and shifting gene profiles associated with treatment. In Blood Advances.

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(2022). Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue. In Cell Metabolism.

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(2022). Single-cell transcriptional profiling of murine conjunctival immune cells reveals distinct populations expressing homeostatic and regulatory genes. In *Mucosal Immunology.

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(2022). IL-17 Producing Lymphocytes Cause Dry Eye and Corneal Disease With Aging in RXRα Mutant Mouse. In Frontiers in medicine.

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(2021). Natural and Synthetic Estrogens in Chronic Inflammation and Breast Cancer. In Cancers.

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(2021). TIFAB accelerates MLL-AF9− Induced acute myeloid leukemia through upregulation of HOXA9. In iScience.

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(2021). Updates on Immunotherapy and Immune Landscape in Renal Clear Cell Carcinoma. In Cancers.

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(2021). CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. In Nature Communications.

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(2021). Hypoglycemia secondary to insulinoma masking the onset of type 1 diabetes in an adolescent. In Clinical case reports.

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(2021). Comprehensive immunologic evaluation of bronchoalveolar lavage samples from human patients with moderate and severe seasonal influenza and severe COVID-19. In The Journal of Immunology.

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(2021). Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells. In Cell Reports.

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(2021). The GPR171 pathway suppresses T cell activation and limits antitumor immunity. In Nature Communications.

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(2021). SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2. In Immunity.

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(2021). TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. In eLife.

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(2021). Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells. In Nature Communications.

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(2021). Mapping the immune environment in clear cell renal carcinoma by single-cell genomics. In Communications Biology.

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(2021). The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent. In Scientific Reports.

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(2021). AP-2γ Is Required for Maintenance of Multipotent Mammary Stem Cells. In Stem Cell Reports.

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(2021). Understanding and targeting human cancer regulatory T cells to improve therapy. In T Regulatory Cells in Human Health and Diseases.

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(2020). Repurposing Anti-Cancer Drugs for COVID-19 Treatment. In Drug Design, Development and Therapy.

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(2020). IL-12-induced immune suppressive deficit during CD8+ T-cell differentiation. In Frontiers in immunology.

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(2020). Multivariable Analysis of 169 Cases of Advanced Cutaneous Melanoma to Evaluate Antibiotic Exposure as Predictor of Survival to Anti-PD-1 Based Immunotherapies. In Antibiotics.

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(2020). A transcriptomic map of murine and human alopecia areata. In JCI Insights.

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(2020). Therapeutic potential of combining PARP inhibitor and immunotherapy in solid tumors. In Frontiers in oncology.

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(2020). Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling. In Oncogene.

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(2020). IL-1 Signaling in Tumor Microenvironment. In Tumor Microenvironment.

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(2020). Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion. In Blood.

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(2020). A TFAP2C Gene Signature Is Predictive of Outcome in HER2-Positive Breast Cancer. In Molecular Cancer Research.

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(2019). Identification of novel TGF-β regulated genes with pro-migratory roles. In Biochimica et Biophysica Acta.

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(2019). Metadherin enhances vulnerability of cancer cells to ferroptosis. In Cell Death and Disease.

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(2019). ROR1 Potentiates FGFR Signaling in Basal-Like Breast Cancer. In Cancers.

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(2019). Single-Cell Profiling of Cutaneous T-Cell Lymphoma Reveals Underlying Heterogeneity Associated with Disease Progression. In Clinical Cancer Research.

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(2019). Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4. In Oncogene.

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(2018). The clinical promise of immunotherapy in triple-negative breast cancer. In Cancer Management and Research.

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(2018). An autoimmune disease risk SNP, rs2281808, in SIRPG is associated with reduced expression of SIRPγ and heightened effector state in human CD8 T-cells. In Scientific Reports.

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(2018). Re-Evaluating E-Cadherin and β-Catenin: A Pan-Cancer Proteomic Approach with an Emphasis on Breast Cancer. In The American Journal of Pathology.

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(2018). Keeping Tumors in Check: A Mechanistic Review of Clinical Response and Resistance to Immune Checkpoint Blockade in Cancer. In Journal of Molecular Biology.

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(2018). A novel HER2 gene body enhancer contributes to HER2 expression. In Oncogene.

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(2018). Stabilization of NF-κB-Inducing Kinase Suppresses MLL-AF9-Induced Acute Myeloid Leukemia. In Cell Reports.

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(2016). Obesity-associated NLRC4 inflammasome activation drives breast cancer progression. In Nature Communications.

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(2016). Calpain-5 expression in the retina localizes to photoreceptor synapses. In Investigative ophthalmology & visual science.

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(2015). Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells. In Cancer Research.

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(2015). Characterization of a novel mouse model with genetic deletion of CD177. In Protein Cell.

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(2014). NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas. In PLoS One.

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(2014). Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade. In PNAS.

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(2014). ROR1, an embryonic protein with an emerging role in cancer biology. In Protein Cell.

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(2013). Dietary resistant starch prevents urinary excretion of 25-hydroxycholecalciferol and vitamin D-binding protein in type 1 diabetic rats. In The Journal of nutrition.

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(2013). A NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1. In Cancer Cell.

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